Full-field electroretinogram in evaluation of the outer retina in patients with multiple sclerosis

Background: Optic nerve inflammation may contribute to the pathology of multiple sclerosis (MS) (retrograde trans-synaptic degeneration) However, within past ten years, some investigations have indicated that primary retinopathy be brought on by MS. This study used a full-field electroretinogram test function outer retinal layers in people with relapsing remitting (RRMS) (ff-ERG). Methods: is case- control study, conducted 30 RRMS patients and healthy controls. were subjected neurological, ophthalmological, radiological assessment. Both controls full field ERG. Results: The ff-ERG showed significant delay latencies b-waves both light dark-adapted condition reduction their amplitudes compared control. ERG responses significantly affected MS or without optic neuritis Most parameters non statistically difference between non-optic eyes. Conclusion: There functional affection bipolar photoreceptors retina eyes Therefore, could site for MS, unrelated affection.